Actos has been prescribed and used by patients in assisting the treatment of Type 2 diabetes by maintaining glucose levels for more than a decade. The generic brand name for this medicine is Pioglitazone, and it has remained a popular oral prescription medication in the United States and most of Europe. In 2008, Takeda Pharmaceuticals earned revenues exceeding $2 billion dollars on Actos alone.
As this medication has mainly been used in combination with insulin and additional diabetes remedies, it has also been prescribed in investigational processes to suppress the advancement of pre-diabetic symptoms, in addition to additional involuntary treatments. However, for the purpose of treating Type 2 diabetes, this drug is presently one of the best-marketed prescription medicines in the U.S.
Severe Health Problems
The U.S. Food and Drug Administration distributed reports in 2007 stating that medicines containing Pioglitazone - including Actos and its European versions, Glustin, Glizone and Pioz - were additionally likely to cause myocardial difficulties, including heart attacks and blood clotting. Individuals developing these types of heart issues while using Actos were at no greater risk than people using additional medicines used to treat Type 2 diabetes.
Actos and Bladder Cancer
In recent studies, which were initially recognized by the French for the Safety of Health Products, it was revealed that medications containing Pioglitazone were connected to an elevated chance of bladder cancer in patients using the drugs to treat Type 2 diabetes or other health issues. The FDA agreed with all reports distributed by similar European agencies, and physicians were soon alerted that by giving patients prescriptions for Actos, they could be exposing individuals to severe health problems.
Takeda Pharmaceuticals performed a study that lasted for five years, revealing that any patient who had used Actos for 12 months of longer were at a higher risk of getting bladder cancer than individuals who had only used the medicine for a short time, or had never used Actos. In spite of these details, doctors continue to prescribe Actos to patients in the U.S.; however, the drug is not prescribed to individuals who presently have serious heart issues or a family medical history of heart conditions. Physicians have also ceased prescribing the medication to patients with bladder cancer.
Actos Side Effects Overview
As with most medications, Actos can feature a variety of side effects, including:
- Abdomen pain
- Breathing troubles such as shortness of breath or labored breathing
- Unexpected weight gain
- Chest pains
- Dryness or feeling excessively thirsty
The more severe side effects consist of:
- Inflammation of limbs or tissues
- Water retention
- Congestive heart disease
The additional side effects of Actos can range from general and mild to critical and fatal. Side effects differ amongst diverse patients and are contingent on numerous factors, including present health condition, past family medical history and an individual’s way of living. If you have encountered any side effects while using Actos or additional types of drugs containing Pioglitazone, you ought to confer with your doctor at once.
What are the Common Bladder Cancer Symptoms?
If a relative has a medical history of specific illnesses such as heart disease or bladder cancer, it is recommended that you avoid taking Actos. Your doctor ought to know about your family history prior to prescribing any drugs. If you are presently taking this medication, common bladder cancer symptoms can be indicated by the following symptoms:
- Serious back pain
- Urinating often
- Feeling pain while urinating
- Blood in your urine
- Disbursing small amounts of urine despite serious urges
- Orange or pink tint to urine color
If you have encountered any or all of the above symptoms, you should consult with your physician.
Legal Options and Just Compensation
If you or a family member has used Actos as a prescribed treatment for Type 2 diabetes and you have encountered or developed critical health problems as a result or developed symptoms of bladder cancer, you should confer with your doctor as soon as possible.
Additionally, you should meet with a qualified attorney. You have legal rights and may be eligible for compensation to assist with your pain, suffering and medical costs, and possibly to help with living expenses, in addition to lost earnings resulting from missing work.